The Davistown Museum

(Nancy Kaufman) #1
such as conjugation and transformation, might take place during the retention of
food residues in the oral cavity.”

Welch, T. J., Fricke, W. F., McDermott, D. G., et al. (2007). Multiple antimicrobial
resistance in plague: an emerging public health risk. PLOS One. 3. pg. 1-6.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000309



  • “Yersinia pestis, the etiological agent of plague, is a zoonotic bacterial pathogen
    that has caused multiple pandemics resulting in an estimated 200 million human
    deaths.”

  • “Plague has recently been recognized as a re-emerging disease as small
    outbreaks continue to occur globally. This reappearance, coupled with its
    potential for aerosol dissemination and associated high mortality rate, also makes
    Y. pestis one of the most dangerous bioterrorism agents.”

  • “Plasmid-positive strains were isolated from beef, chicken, turkey and pork, and
    were found in samples from the following states: California, Colorado,
    Connecticut, Georgia, Maryland, Minnesota, New Mexico, New York and
    Oregon...this common plasmid backbone is broadly disseminated among MDB
    zoonotic pathogens associated with agriculture.”


Wellington, E., et al. (2013). The role of the natural environment in the emergence of
antibiotic resistance in Gram-negative bacteria. Lancet: Infectious Disease. 13(2). pg.
155-65. http://www.ncbi.nlm.nih.gov/pubmed/23347633



  • “During the past 10 years, multidrug-resistant Gram-negative Enterobacteriaceae
    have become a substantial challenge to infection control.”

  • “The effectiveness of antibiotics is in such rapid decline that, depending on the
    pathogen concerned, their future utility can be measured in decades or even
    years. Unless the rise in antibiotic resistance can be reversed, we can expect to
    see a substantial rise in incurable infection and fatality in both developed and
    developing regions.”

  • “The selective effects of pollutants an co-select for mobile genetic elements
    carrying multiple resistant genes. Anthropogenic activity might be causing
    evolution of antibiotic resistance in the environment.”

  • “As the human population increases, and mega cities grow, there is greater risk
    that infectious diseases will evolve, emerge, or spread readily among the most
    substantial reservoir of multidrug-resistant Gram-negative bacilli
    (Enterobacteriaceae and Pseudomonas aeuginosa) is the gut of man and
    animals.”

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