- “Many resolutions and recommendations have been propounded, and numerous
reports have been written, but to no avail: the development of antibiotic
resistance is relentless.” - “Antibiotics have revolutionized medicine in many respects, and countless lives
have been saved; their discovery was a turning point in human history.
Regrettably, the use of these wonder drugs has been accompanied by the rapid
appearance of resistant strains.” - “Stricter measures in infection control and antibiotic use [include] efforts to
prevent dumping of antibiotics into the environment through sewer systems
complete destruction of antibiotics before disposal should be common practice.” - “The tragedy is that most pharmaceutical companies are now shirking the
responsibilities of their own business missions. The onus is on academia to
furnish information on the multifunctional aspects of microbial network
interactions that will provide the discovery tools of the future.”
Davis, M. F. and Rutkow, L. (2012). 327 Regulatory strategies to combat antimicrobial
resistance of animal origin: Recommendations for a science-based U.S. approach.
Tulane Environmental Law Journal. 25(327). pg. 1-55.
http://www.jhsph.edu/research/centers-and-institutes/johns-hopkins-center-for-a-
livable-future/_pdf/research/clf_reports/Davis%20Regulatory%20Strategies.pdf
- “This article presents an update pertaining to nontherapeutic use of
antimicrobials in livestock and to surveillance of antimicrobial-resistant
pathogens of food animal origin.”
D’Costa, V. M., McGrann, K. M., Hughes, D. W. and Wright, G. D. (2006). Sampling
the antibiotic resistome. Science. 311(5759). pg. 374-7.
http://www.ncbi.nlm.nih.gov/pubmed/16424339
- “Microbial resistance to antibiotics currently spans all known classes of natural
and synthetic compounds. It has not only hindered our treatment of infections but
also dramatically reshaped drug discovery, yet its origins have not been
systematically studied. Soil-dwelling bacteria produce and encounter a myriad of
antibiotics, evolving corresponding sensing and evading strategies. They are a
reservoir of resistance determinants that can be mobilized into the microbial
community. Study of this reservoir could provide an early warning system for
future clinically relevant antibiotic resistance mechanisms.”
Domenech, B., Munoz, M., Muraviev, D. N. and Macanas, J. ( 2013 ). Polymer-Silver
nanocomposites as antibacterial materials. Microbiology. 4(1). pg. 630-40.
http://www.formatex.info/microbiology4/vol1/630-640.pdf