- “Here we report a new antibiotic that we term teixobactin, discovered in a screen
of uncultured bacteria.” - “We did not obtain any mutants of Staphylococcus aureus or Mycobacterium
tuberculosis resistant to teixobactin. The properties of this compound suggest a
path towards developing antibiotics that are likely to avoid development of
resistance.”
Livermore, D. M., Canton, R., Gniadkowski, M., et al. (2007). CTX-M: Changing the
face of ESBLs in Europe. Journal of Antimicrobial Chemotherapy. 59. pg. 165-74.
http://jac.oxfordjournals.org/content/59/2/165.full
- “Since around 2000—earlier in Poland and Spain and later in France and the
UK—dramatic shifts have occurred in the prevalence and types of extended- β-
lactamases (ESBLs) in Europe.” - “Subsequently, CTX-M ESBLs have become dominant, with many infections in
‘complicated community’ patients, usually with underlying disease, recent
antibiotic usage, or healthcare contact.” - “Irrespective of the particular enzyme, most producers are multiresistant. These
changing patterns present major therapeutic and infection control challenges,
with the public health intervention points unclear.” - “I t is clear that Europe is moving to a situation where ESBLs are more common
and less confined to hospitals, as well as one where E. coli is a major host
species. If so, the opportunities for control are disturbingly small.”
Loffler, C., Bohmer, F., Hornumg, A., et al. (2014). Dental care resistance prevention
and antibiotic prescribing modification – the cluster-randomised controlled DREAM
trial. Implementation Science. 9(27). pg. 1-66.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936853/
- “In Europe, dentistry accounts for a comparatively high amount of antibiotic
prescriptions.” - “We expect the results of this trial to have a major impact on antibiotic
prescription strategies and practices in Germany.”
Lubick, N. (2011). Antibiotic resistance shows up in India’s drinking water. Nature.
Nature/doi:10.1038/news.2011.218.
- “Bacteria carrying a gene that confers resistance to a major class of antibiotics
have shown up in samples of drinking water and sewage seepage from New
Delhi, researchers report in The Lancet Infectious Diseases today...This is the