The Davistown Museum

(Nancy Kaufman) #1

Pfaller, M. A. and Diekema, D. J. (2004). Rare and emerging opportunistic fungal
pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus.
Journal of Clinical Microbiology. 42(10). pg. 4419-31.
http://jcm.asm.org/content/42/10/4419.full



  • “The frequency of invasive mycoses due to opportunistic fungal pathogens has
    increased significantly over the past two decades...Serious life-threatening
    infections are being reported with an ever increasing array of pathogens,
    including the well-known opportunists Candida albicans, Cryptococcus
    neoformans, and Aspergillus fumigatus.”


Podolsky, S. H. (2014). The antibiotic era; reform, resistance, and the pursuit of a
rational therapeutic. Johns Hopkins University Press, Baltimore, MD.


Pollack, A. (February 27, 2010). Rising threat of infections unfazed by antibiotics. The
New York Times. pg. B-1.
http://www.nytimes.com/2010/02/27/business/27germ.html?_r=0



  • “The bacteria [Acinetobacter] classified as Gram-negative because of their
    reaction to the so-called gram stain test, can cause severe pneumonia and
    infections of the urinary tract, bloodstream and other parts of the body. Their cell
    structure makes them more difficult to attack with antibiotics than gram-positive
    organisms like MRSA.”

  • “Meanwhile, New York City hospitals, perhaps because of the large number of
    patients they treat, have become the global breeding ground for another drug-
    resistant gram-negative germ, Klebsiella pneumoniae.”

  • “MRSA remains the single most common source of hospital infections...it can
    also infect people outside the hospital.”

  • “By comparison, the drug-resistant gram-negative germs for the most part
    threaten only hospitalized patients whose immune systems are weak. The germs
    can survive for a long time on surfaces in the hospital and enter the body through
    wounds, catheters and ventilators.”


Projan, S. J. (2003). Why is Pharma getting out of antibacterial drug discovery? Current
Opinion in Microbiology. 6. pg. 427-30.
http://www.ncbi.nlm.nih.gov/pubmed/14572532


Pruden, A., Pei, R., Storteboom, H. and Carlson, K. (2006). Antibiotic resistance genes
as emerging contaminants: Studies in northern Colorado. Environmental Science and
Technology. 40. pg. 7445-50. http://pubs.acs.org/doi/abs/10.1021/es060413l



  • This study explores antibiotic resistance genes (ARGs).

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