develop resistance to triclosan and the current view that triclosan may have a
specific target in Escherichia coli, namely enoyl reductase, underline the need for
more research on the mechanisms of action and resistance.”
Szcepanowski, R., Krahn, I., Linke, B., et al. (2004). Antibiotic multiresistance plasmid
pRSB101 isolated from a wastewater treatment plant is related to plasmids residing in
phytopathogenic bacteria and carries eight different resistance determinants including a
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http://www.ncbi.nlm.nih.gov/pubmed/15528650
Szcepanowskic, R., Braun, S., Riedel, V., et al. (2005). The 120 592 bp IncG plsdmif
pTDN107 isolated from a sewage-treatment plant encodes nine different antibiotic-
resistance determinants, two iron-acquisition systems and other putative virulence-
associated functions. Microbiology. 151. pg. 1095-111.
http://www.ncbi.nlm.nih.gov/pubmed/15817778
Szewzyk, U., Szewyk, R. and Manz, W. (2000). Microbiological safety of drinking
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cro
Tenover, F. SEE SKIP FOR CITATION. Development and spread of bacterial
resistance to antimicrobial agents: An overview.
- “Twenty years ago, bacteria that were resistant to antimicrobial agents were easy
to detect in the laboratory because the concentration of drug required to inhibit
their growth was usually quite high and distinctly different from that of
susceptible strains.” - “Emerging resistance has required adaptations and modifications of laboratory
diagnostic techniques, empiric anti-infective therapy for such diseases as
bacterial meningitis, and infection control measures in health care facilities of all
kinds. Judicious use is imperative if we are to preserve our arsenal of
antimicrobial agents into the next decade.” - “As of 2016, our arsenal of antimicrobial agents, with one possible exception
(SEE SKIP FOR CITATION) no longer exists.”
Teuber, M. (2001). Veterinary use and antibiotic-resistance. Current Opinion in
Microbiology. 4. pg. 493-9. http://www.ncbi.nlm.nih.gov/pubmed/11587923
- “Globally, an estimated 50% of all antimicrobials serve veterinary purposes.
Bacteria that inevitably develop antibiotic resistance in animals comprise food-
borne pathogens, opportunistic pathogens and commensal bacteria. The same
antibiotic resistance genes and gene transfer mechanisms can be found in the