Addiction Medicine: Closing the Gap between Science and Practice

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Chapter III


Prevalence and Consequences


More than one in seven (15.9 percent, 40.3
million) people in the United States ages 12 and
older currently meet clinical criteria for
addiction* 1 --more than the share of the
population with cancer, diabetes or heart
disease.† 2 An additional but unknown number
of people have the disease but are managing it
effectively and so do not meet these behavioral
criteria.‡ 3 Another third of the population (31.7
percent, 80.4 million), while not addicted,
currently§ use one or more addictive substances
in ways that threaten their own health and safety
or the health and safety of others.^4

Risky substance use and addiction are the largest
preventable and most costly public health and
medical problems in the U.S.^5 Together they are
the leading causes of preventable death and
cause or contribute to more than 70 other
conditions requiring medical care.^6 The
damaging effects of risky substance use and
addiction extend to a wide range of costly social

* Defined as meeting criteria for past-month nicotine
dependence based on the Nicotine Dependence
Syndrome Scale (NDSS) and meeting diagnostic
criteria for past year alcohol and/or other drug abuse
or dependence (excluding nicotine) in accordance
with the Diagnostic and Statistical Manual of Mental
Disorders (DSM-IV). (The DSM refers to substance
abuse and substance dependence collectively as
substance use disorders. The criteria for nicotine
dependence in the NDSS parallel those of the DSM-
IV.) This estimate excludes the institutionalized
population, for which rates of addiction are higher.
† Includes coronary heart disease, angina pectoris,
heart attack or any other heart condition or disease,
excluding hypertension and stroke.
‡ There are no national data on the proportion of the
population that has been diagnosed with addiction
and is effectively managing the disease. Existing
national survey data indicate that 10 percent of adults
ages 18 and older report that they “once had a
problem with drugs or alcohol but no longer do”
(sometimes referred to as “sustained recovery”), but
it is not clear what proportion of this group ever was
diagnosed with addiction as distinguished from
“having a problem.”
§ In the past 30 days.
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