Addiction Medicine: Closing the Gap between Science and Practice

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Four out of every 10 (39.6 percent) fatal traffic
crashes involve a driver who is under the
influence of alcohol* or who tested positive for
other drugs.^99


Overdose deaths caused by controlled
prescription drugs and illicit drugs have
increased five-fold since 1990^100 and now
surpass the total number of deaths caused by
traffic accidents.^101


Individuals with addiction are at increased risk
of potentially fatal diseases including cancer,^102
heart disease^103 and sexually-transmitted
diseases.^104 More specifically, smoking
contributes to multiple types of cancer as well as
heart and respiratory disease.^105 Alcohol
contributes to some of the leading causes of
death, including heart disease, cancer and stroke,
as well as to other serious illnesses such as
cirrhosis, hepatitis and pancreatitis.^106 Injection
drug use contributes to HIV, hepatitis C and
hepatitis B.^107 CASA Columbia’s research
found that risky substance use and addiction
cause or contribute to more than 70 other
conditions requiring medical care, including
cancer, respiratory disease, cardiovascular
disease, pregnancy complications, HIV/AIDS,
cirrhosis, ulcers and trauma.^108 (See Table 3.9)



  • Has a blood alcohol concentration of 0.08 or higher.


The many negative consequences of our failure
to prevent risky substance use and treat
addiction extend beyond the individual to
family, friends, community and society.^109
Risky substance use and untreated addiction
contribute to family dysfunction and financial
troubles, disrupted social relationships, unsafe
sexual practices, unplanned pregnancies, lost
work productivity, legal problems, poor
academic and career performance,
homelessness, property and violent crimes,
domestic violence, child abuse and neglect,
rapes and other sexual assaults and motor
vehicle crashes and fatalities.^110

Risky substance use and addiction adversely
affect the mental health of other family members
as well. Family members ages 19 and older are
at approximately twice the risk of having
addiction or clinical depression as those ages 19
and older in families without a member with
addiction, and they have higher health care
costs.^111

Children and adolescents are particularly
vulnerable to the health consequences of
substance use.^112 Approximately 70 percent of
child welfare cases are caused or exacerbated by
parental risky use and addiction.^113 Children
exposed to parental substance use are at
increased risk of emotional and behavioral
problems, conduct disorder, poor developmental
outcomes and risky substance use and addiction
in adolescence and adulthood.^114 Children and
adolescents with family members who have
addiction are more likely to be diagnosed with a
number of medical conditions, including asthma,
depression, headaches, attention deficit/
hyperactivity disorder, trauma and addiction,
than children in families of similar demographic
characteristics who do not have a member with
addiction.^115

Table 3.8
Deaths Attributable to Substance Use

Deaths/Year
Total Deaths Attributable to
Substance Use


578,819

Tobacco 443,000
Alcohol 98,334
Other drugs 37,485*



  • Based on data from 2009.


Sources: Tobacco--Centers for Disease Control and
Prevention (2008); Alcohol--CASA Columbia
analysis of the Alcohol and public health: Alcohol-
Related Disease Impact (ARDI) (2012); Other
Drugs--Centers for Disease Control and Prevention
(2010); Kochanek, K., et al. (2011).

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