Severalreviews(Wang,2002;Reyes et al., 2002; Aurouxet al., 2002;
Sheehanet al., 2003;Vilkneret al., 2004)describe statusquo,recent develop-
mentsand advantages of thesesystems. Theyillustrate that the advantagesof-
TAS are speed, high performance, versatility, negligible sample/reagent
consumption and automation.
Themajority of research work in this area has been directed toward
biological and medicalsciences;examples are (Aurouxet al., 2002):cell culture
and cell handling, clinical diagnostics, immunoassays, proteins,DNAseparation
and analysis, polmerasechainreaction(PCR). Direct applications for food
hygiene/foodsafetyare not availableyet.
19.4 References
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Bioelec., 18 , 841±846.
AMPUEROS, BOSSETJO(2003),Theelectronicnoseappliedto dairyproducts:a review', Sens.Actuators,B94, 1±12. ARNOLDMA,MEYERHOFFME(1988),Recentadvancesin the developmentand analytical
applicationsof biosensingprobes',Crit.Rev.Anal.Chem., 20 , 149±196.
ARTURSSON T, EKLO»V T, LUNDSTRO»M I, MA^ RTENSSON P, SJO»STRO»M M, HOLMBERG M(2000),
Driftcorrectionfor gas sensorsusingmultivariatemethods',J. Chemom., 14 , 711±723. AUROUXPA,IOSSIFIDISD, REYESDR,MANZA(2002),Micrototalanalysissystems.2.
Analyticalstandardoperationsand applications',Anal.Chem., 74 , 2637±2652.
BACHINGER,T, HAUGENJE(2003).`Processmonitoring',in PearceTC, SchiffmanSS,
Nagle HT, Gardner JW, Machine olfaction, Electronic nose technology,
Weinheim,Wiley-VCH,481±503.
Fig. 19.6 Schematicconstructionof a `lab on a chip'withthreedifferentminiaturised
techniques± the chemicalinformationis transformedinto opticaland electronic
information.
Improvinghygieniccontrol by sensors 301