References
Adibi, S.A. (1997) Renal assimilation of oligopeptide: physiological mechanisms and metabolic
importance. American Journal of Physiology272, E723–E736.
Arriza, J.L., Eliasof, S., Kavanaugh, M.P. and Amara, S.G. (1997) Excitatory amino acid transporter 5,
a retinal glutamate transporter coupled to a chloride conductance. Proceedings of the National
Academy of Sciences of the United States of America94, 4155–4160.
Backwell, C., Wilson, D. and Schweizer, A. (1995) Evidence for a glycyl-proline transport system in
ovine enterocyte brush-border membrane vesicles. Biochemical and Biophysical Research
Communications 215, 561–565.
Boll, M., Herget, M., Wagener, M., Weber, W.M., Markovich, D., Biber, J., Clayton, D.F., Murer, H. and
Daniel, H. (1996) Expression cloning and functional characterization of the kidney cortex high-
affinity proton-coupled peptide transporter. Proceedings of the National Academy of Sciences of
the United States of America93, 284–289.
Boyd, C.A.R. (1995) Intestinal oligopeptide transport. Proceedings of the Nutrition Society54,
519–523.
Brandsch, M., Brandsch, C., Ganapathy, M.E., Chew, C.S., Ganapathy, V. and Leibach, F.H. (1997)
Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide
cotransport systems in intestine (PEPT1) and kidney (PEPT2). Biochimica et Biophysica Acta
1324, 251–262.
Brandsch, M., Thunecke, F., Kuller, G., Schutkowski, M., Fischer, G. and Neubert, K. (1998) Evidence
for the absolute conformational specificity of the intestinal H+/peptide symporter, PEPT1.
Journal of Biological Chemistry273, 3861–3864.
Calonge, M.L., Ilundain, A. and Bolufer, J. (1990) Glycyl-L-sarcosine transport by ATP-depleted isolated
enterocytes from chicks. American Journal of Physiology259, G775–G780.
Christensen, H.N. (1984) Organic ion transport during seven decades. Biochimica et Biophysica Acta
779, 255–269.
Daniel, H., Morse, E.L. and Adibi, S.A. (1992) The high and low affinity transport systems for
dipeptides in kidney brush border membrane respond differently to alterations in pH gradient
and membrane potential. Journal of Biological Chemistry266, 19917–19924.
Deves, R. and Boyd, C.A.R. (1998) Transporters for cationic amino acids in animal cells: discovery,
structure, and function. Physiology Reviews78, 487–545.
Duke, G.E. (1984) Avian digestion. In: Swenson, M.J. (ed.) Dukes’ Physiology of Domestic Animals.
Cornell University Press, Ithaca, Vol. 10, pp. 359–366.
Dyer, J., Allison, G., Scollan, N.D. and Shirazi-Beechey, S.P. (1996) Mechanism of peptide transport
in ruminant intestinal brush-border membrane. Biochemical Society Transactions24, 247S.
Fei, Y.-J., Kanai, Y., Nussberger, S., Ganapathy, V., Leibach, F.H., Romero, M.F., Singh, S.K., Boron,
W.F. and Hediger, M.A. (1994) Expression cloning of a mammalian proton-coupled oligopeptide
transporter. Nature368, 563–566.
Ganapathy, V., Brandsch, M. and Leibach, F.H. (1994) Intestinal transport of amino acids and peptides.
In: Johnson, L.R. (ed.) Physiology of the Gastrointestinal Tract, 3rd edn. Raven Press, New York,
pp. 1773–1794.
Ganapathy, M.E., Huang, W., Ganapathy, V. and Leibach, F.H. (1998) Valacyclovir: a substrate for the
intestinal and renal peptide transporters PEPT1 and PEPT2. Biochemical and Biophysical
Research Communications246, 470–475.
Gardner, M.L.G. (1994) Absorption of intact proteins and peptides. In: Johnson, L.R. (ed.) Physiology of
the Gastrointestinal Tract, 3rd edn. Raven Press, New York, pp. 1795–1820.
Guerino, F. and Baumrucker, C.R. (1987) Identification of methionine and lysine transport systems in
cattle small intestine. Journal of Animal Science65, 630–640.
Haussinger, D. (1990) Nitrogen metabolism in liver: structural and functional organization and
physiological relevance. Biochemical Journal267, 281–290.
Johns, J.T. and Bergen, W.G. (1973) Studies on amino acid uptake by ovine small intestine. Journal of
Nutrition103, 1581–1586.
Kilberg, M.S. and Haussinger, D. (1992) Mammalian Amino Acid Transport: Mechanisms and
Control. Plenum Press, New York.
Leibach, F.H. and Ganapathy, V. (1996) Peptide transporters in the intestine and the kidney. Annual
Review of Nutrition16, 99–119.
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