Table 2.1 lists the model parameters
and the fractional transfer rates (Li,jfrom
compartment j to i). The fractional standard
deviation of the parameters ranges from 5
to 50% and, in general, L2,1, L1,2and L0,1or
L0,3are solved with a higher precision than
40 J.A. Rathmacher
1.000
0.100
0.010
0.001
Tracer to tracee ratio
0 1 2 3 4 5
Cattle, human and dog model
Observed Calculated
(A)
Time (min 1000)
0.100
0.010
0.001
Tracer to tracee ratio
0 1 2 3 4 5
Sheep model
Observed Calculated
(B)
Time (min 1000)
1.000
0.100
0.010
0.001
Tracer to tracee ratio
0 1 2 3 4 5 6
Swine model
Observed Calculated
(C)
Time (min 1000)
Fig. 2.10.Disappearance of tracer, 3-[^2 H 3 -methyl]methylhistidine, as the ratio of 3-[^2 H 3 -methyl]methylhisti-
dine to 3-methylhistidine in plasma as described by a three-compartment model of 3-methylhistidine (see