Pancreatic Hormones Clinical Chemistry Review 114
HORMONE REGULATES COMMENTS
Insulin Carbohydrate metabolism Produced in beta cells of islets of Langerhans. Causes ↑movement of
glucose into cells for metabolism. Decreases plasma glucose levels. ↓in
diabetes mellitus, ↑with insulinoma, hypoglycemia.Glucagon Glycogenolysis, gluconeogenesis, lipolysis Produced in alpha cells of islets of Langerhans. Increases plasma glucose
levels. ↑with glucagonoma, diabetes mellitus, pancreatitis, trauma.