Bacterial Toxins Clinical Microbiology Review 141
EXOTOXIN ENDOTOXIN
Produced by Gram positives Gram negatives
Location in cell Within & without Within
Composition Protein Lipopolysaccharide
Effect Systemic Local
Toxicity High Low
Stability to heating Unstable Stable
Antigenicity High Low
Stimulates antitoxin productions? Yes No
Converted to toxoid? Yes No