Neisseriaand Moraxella Clinical Microbiology Review 173
ORGANISM PATHOGENICITY GRAM STAIN CULTURE KEY CHARACTERISTICS OTHER
Neisseriaspp
N. gonorrhoeae Susceptible to drying
& cold. Don’t refrig-
erate specimens.
Molecular methods
for genital speci-
mens. Culture
preferred for non-
genital specimens &
those from children.
Should confirm by
different method.
Aerobic or faculta-
tive. Pathogens are
capnophilic.Requires ↑CO 2. Usu-
ally doesn’t grow on
SBA. Grows on CHOC
& Neisseria-selective
media. Colonies are
small, grayish white
or tan. 5 different
colony types. May
look like mixed
culture.See individual
organisms belowGonorrhea, salpingi-
tis, ophthalmia of
the newbornGNDC, coffee-
bean shapedIntracellular & ex-
tracellular GNDC.
Diagnostic in
urethral discharge
from sympto-
matic males.
Culture confirma-
tion required for
femalesCatalase pos. Oxidase pos.Carbohydrate utilization:
glucose only. Superoxol
pos. Can ID with mono-
clonal antibodies.continued...