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Gram-Negative Anaerobes Clinical Microbiology Review 206


ORGANISM PATHOGENICITY GRAM STAIN OTHER

Gram-negative cocci
Veillonella

Gram-negative rods
Bacteroides fragilis

Fusobacterium

Porphyromonas

Prevotella

May show weak red fluorescence under
UV light. Doesn’t grow on KVLB. Usually
doesn’t reduce nitrates.

Most common anaerobe isolated.
Resistant to bile. Hydrolyses esculin.
Turns BBE brown.

Indole pos. Most fluoresce chartreuse
(green-yellow) under UV light.

Slow growing. Brown to black on SBA.
Some fluoresce brick-red to orange
under UV light. Doesn’t grow on KVLB.

Slow growing. Some are pigmented.
Brown to black on SBA & KVLB. Some
fluoresce brick-red to orange under UV
light. Doesn’t grow on BBE.

Normal flora of upper respiratory
tract, GI & GU tracts. Usually in
mixed culture. Can cause infec-
tions in immunocompromised

Mixed infections below
diaphragm

Pulmonary infections, brain
abscesses, oral lesions

Head, neck, & pleuropulmonary
infections

Head, neck, & pleuropulmonary
infections

Tiny GNDC in pairs, clusters,
short chains. Can resemble
Neisseria

Pleomorphic, pale, irregu-
larly staining GNR

GNR. F. nucleatumis long &
thin with tapered ends
(spindle shaped)

GNCB

GNCB
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