Differentiation ofPlasmodiumcontinued Clinical Microbiology Review 264
P. FALCIPARUM P. MALARIAE P. OVALE P. VIVAX
Multiple parasites
per cell?Double chromatin
dots?Other characteristicsNote: A 5th species, P. knowlesi, now recognized. Can resemble P. malariae or P. falciparum. Differentiate by PCR.
RareRareMost common. Rarely fatal.
May cause relapsesYesYesHigh mortality. Medical
emergencyNoNoRarely fatal. Band-
shaped trophsNoNoLeast common. Rarely
fatal. May cause relapses(From Leventhal R, Cheadle RF. Medical
Parasitology: A Self-Instructional Text,
5th ed. Philadelphia: FA Davis; 2002:118.)