Tests of Fibrinolytic System Hematology Review 358
TEST EXPLANATION METHOD(S) CLINICAL SIGNIFICANCE
D-dimer Fragment that results from Latex agglutination using Marker for DIC. Also pos with deep vein
lysis of fibrin by plasmin monoclonal antibodies against thrombosis, pulmonary embolism, & after
D-dimer, ELISA lytic therapy. Neg in primary fibrinolysis.
Fibrin(ogen) Product of action of plasmin Latex agglutination using Sign of ↑fibrinolytic activity. Doesn’t
degradation on fibrin or fibrinogen antibodies against FDP differentiate between fibrin degradation
products (FDP) products & fibrinogen degradation products.
Present in DIC, primary fibrinolysis, deep vein
thrombosis, pulmonary embolism, & after
lytic therapy.
