Quick Review Cards for Medical Laboratory Science

Cells of the Natural Immune System Immunology Review 375

CELL

Granulocytes
Neutrophils

Eosinophils

Basophils

Mononuclears
Monocytes

Tissue cells
Mast cells

Macrophages

Dendritic cells

FUNCTION

Phagocytosis, inflammatory response

Neutralization of basophil & mast cell

products

Destruction of some helminths

Hypersensitivity rxn

Phagocytosis

Hypersensitivity rxn

Phagocytosis; elimination of bacteria, intra -

cellular parasites, tumor cells; secretion of

cell mediators; ag presentation

Phagocytosis, presentation of ag to helper T

lymphs in blood & lymphoid organs

COMMENTS

Respond to chemotaxins. Granules contain bactericidal enzymes.

Some phagocytic ability.

Granules contain histamine, heparin, eosinophil chemotactic factor A.

In allergic rxn, bind IgE. Granules release contents in presence of ag.

Migrate to tissues, become macrophages. Respond to chemotaxins.

Connective tissue cells. Resemble basophils but larger & more

granules. Bind IgE.

Activated by contact with microorganisms or cytokines from T

lymphs.

Initiate acquired immune response.

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