Quick Review Cards for Medical Laboratory Science

Immunoglobulins Immunology Review 383

Form

Molecular
weight
(daltons)

Heavy chain

Light chain

% of total Ig

Serum
concentration
(mg/dL)

Antigen-
binding
sites

Complement
fixation

IgG

Monomer

150,000

Gamma (g)

Kappa (k) or

lambda (l)

70–75

800–1,600

2

Yes

IgM

Pentamer

900,000

Mu (m)

kor l

10

120–150

10

Yes

IgA

Monomer & dimer

160,000 or 400,000

Alpha (a)

kor l

10–15

70–350

2 or 4

No

IgD

Monomer

180,000

Delta (d)

kor l

<1

1–3

2

No

IgE

Monomer

190,000

Epsilon (e)

kor l

0.002

0.005

2

No

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