Open and Closed Systems Immunohematology Review 426
EXPLANATION EFFECT ON EXPIRATION DATE OF COMPONENT
Open system
Closed system
Components stored at 1°–6°C must be used within 24 hr
after system opened; components stored at 20°–24°C
within 4 hr.
No change.
Seal on unit is broken to attach external transfer
bag. Exposure to air poses threat of bacterial
contamination.
Sterility maintained through use of attached
satellite bags or sterile connecting device that
welds tubing from 1 bag to another. No exposure
to air.
