Antibody Characteristics Immunohematology Review 456
Naturally occurring
Clinically significant
Warm antibodies
Cold antibodies
Usually only react in AHG
Can react in any phase of testing
Detection enhanced by enzyme treatment of test cells
Not detected with enzyme treatment of test cells
Enhanced by acidification
Show dosage
Bind complement
Cause in vitro hemolysis
Labile in vivo & in vitro
Common cause of anamnestic response (delayed tf rxn)
ABO, Lewis, P 1 , MN, Lua
ABO, Rh, Kell, Duffy, Kidd, SsU
Rh, Kell, Duffy, Kidd
M, N, P 1
Kell, Duffy, Kidd
Lewis
Rh, Lewis, Kidd, P 1
M, N, Duffy
M
Rh other than D, MNS, Duffy, Kidd
I, Kidd, Lewis
ABO, Lewis, Kidd, Vell, some P 1
Kidd
Kidd
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