Crossmatches Immunohematology Review 465
EXPLANATION WHEN PERFORMED COMMENTS
Antiglobulin xmatch
Immediate spin (IS) xmatch
Computer (electronic) xmatch
Detects ABO incompatibility. Ab
screen carried through AHG must
be performed & must be neg.
Detects ABO incompatibility. ABO
typing of recipient must be done
× 2. Ab screen carried through
AHG must be performed & must
be neg. Computer system must
be validated to prevent release of
ABO-incompatible blood & must
alert user to discrepancies &
incompatibilities.
Recipient serum & donor
RBCs tested through AHG
Recipient serum & donor
RBCs tested in IS only
Computer check of donor
ABO & Rh type & recipient
ABO & Rh type
If recipient has or had
clinically significant ab
If recipient doesn’t have
& never had clinically
significant ab
If recipient doesn’t have
& never had clinically
significant ab