Comparison of DNA and RNA
Molecular Diagnostics
(MDx) Review 527
DNA RNA
Function
Location
Composition
Sugar
Pyrimidines
Purines
Converts genetic information from
DNA into proteins. Some has regula-
tory or structural function. Source of
genetic information in RNA viruses.
Nucleus & cytoplasm.
Repeating nucleotides linked by
phosphodiester bonds between
5’ phosphate group of 1 sugar &
3’ hydroxyl group of next.
Ribose.
C, U.
A, G.
Carries genetic information. Serves as template for synthesis of RNA.
Nucleus (except mitochondrial DNA).
Repeating nucleotides linked by phosphodiester bonds between 5’
phosphate group of 1 sugar & 3’ hydroxyl group of next.
Deoxyribose.
C, T.
A, G.
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