DNA Replicationcontinued
Molecular Diagnostics
(MDx) Review 535
Okazaki fragmentsReplication forkOverall direction of replicationDNA
polymeraseLeading strand
Lagging strand5 ′3 ′3 ′5 ′5 ′
3 ′^5 ′^3 ′(From Buckingham L. Molecular Diagnostics: Fundamentals, Methods, and Clinical Applications, 2nd ed.
Philadelphia: FA Davis; 2012:9.)