Quick Review Cards for Medical Laboratory Science

Clinical Applications of Molecular

Diagnosiscontinued

Molecular Diagnostics

(MDx) Review 574

DISCIPLINE APPLICATIONS

Oncology

Other

Dx of cancer, e.g., breast, bladder, lung, colon. KRASmutation in colon cancer predicts lack of response to

certain therapies.

Paternity testing, forensics (DNA fingerprinting), pharmacogenomics (“personalized medicine,” selection of

optimal drug therapy based on patient’s genotype), fetomaternal medicine (circulating DNA & RNA)