Facts on File Encyclopedia of Health and Medicine

There are five identified subtypes of Hodgkin’s lymphoma: lymphocyte-predominant (also called nodular lymphocyte predominance) ...

RADIATION THERAPY, either above the diaphragm only (mantle field radiation) or from the neck to the pelvis (total nodal irradia ...

HIV/AIDS INFECTION with human T-lymphocytic virus 1 (HTLV-1), EPSTEIN-BARR VIRUS, or human her- pesvirus 8 (HHV-8) infection wi ...

M–N megakaryocyte See BONE MARROW. methemoglobinemia A BLOODoxygenation dis- order in which methemoglobin, a structure of HEMOGL ...

therapy may also be appropriate for people who cannot take methylene blue. Recovery is generally complete when the cause is toxi ...

such as occurs with multiple myeloma reduces EPO production, resulting in moderate to signifi- cant ANEMIA. M-proteins can bind ...

presses the maturation of lymphocytes to plasma cells. Thalidomide analogs (such as Revimid and Actimid) are drugs closely relat ...

experts to recommend effective preventive meas- ures. Potential complications of both the multiple myeloma and its treatments pr ...

supplementation to stimulate the remaining red bone marrow to increase its erythrocyte production (erythropoiesis). Occasionally ...

P phagocyteA white BLOODcell (LEUKOCYTE) that consumes pathogens during an IMMUNE RESPONSE called PHAGOCYTOSIS. Granulocytes, an ...

For further discussion of the plasma within the context of blood and lymph structure and func- tion please see the overview sect ...

polycythemia vera A myeloproliferative condi- tion of the BLOODin which the red BONE MARROW produces an excessive volume of eryt ...

R–S reticulocyte An ERYTHROCYTE (red BLOOD cell) that enters the blood’s circulation from theBONE MARROWjust before it has reach ...

ens and hardens the normally flexible erythro- cytes, pulling them into a sickle or crescent shape. The rigidity and inflexibili ...

bin production in some children). BONE MARROW TRANSPLANTATIONis sometimes an option for people who have severe symptoms. There i ...

splenectomy A surgical OPERATIONto remove the SPLEEN. Though the spleen performs many vital immune and BLOOD-related functions, ...

T thalassemia A genetic disorder of the BLOODin which the body fails to produce one or more of the proteins necessary for the sy ...

aside from the intrusion of regular blood transfu- sions, and normal LIFE EXPECTANCY. Beta forms of thalassemia tend to be more ...

phate and the CHEMOTHERAPYagents hydroxyurea and anagrelide. Some people benefit from platelet apheresis, a form of HEMAPHERESIS ...

dispenses the likelihood for developing thrombo- cytopenia. See also DISSEMINATED INTRAVASCULAR COAGULATION (DIC); THROMBOCYTHEM ...