Diazepam 121if their mothers used diazepam during pregnancy; those symptoms may not
appear immediately after birth.
Nursing mothers are advised to avoid the drug, which can continue to pass
into breast milk long after drug use is halted. The drug can build up in babies,
enough that they can be sedated by milk from mothers using diazepam, and
the infants may lose weight while nursing.
Additional information.Methaqualoneand diazepam each have the nick-
name “Ludes,” but the drugs are different substances.
Additional scientific information may be found in:
Clarke, C.H., and A.N. Nicholson. “Immediate and Residual Effects in Man of
the Metabolites of Diazepam.”British Journal of Clinical Pharmacology6 (1978):
325–31.
Giri, A.K., and S. Banerjee. “Genetic Toxicology of Four Commonly Used Benzodiaz-
epines: A Review.”Mutation Research340 (1996): 93–108.
Gotestam, K.G., and B.E. Andersson. “Subjective Effects and Vigilance after Diazepam
and Oxazepam in Normal Subjects.”Acta Psychiatrica Scandinavica19, no. 274
(1978, Suppl.): 117–21.
Griffiths, R.R., et al. “Comparison of Diazepam and Oxazepam: Preference, Liking and
Extent of Abuse.”Journal of Pharmacology and Experimental Therapeutics 229
(1984): 501–8.
Griffiths, R.R., et al. “Relative Abuse Liability of Diazepam and Oxazepam: Behavioral
and Subjective Dose Effects.”Psychopharmacology(Berlin) 84 (1984): 147–54.
Juergens, S. “Alprazolam and Diazepam: Addiction Potential.”Journal of Substance
Abuse Treatment8 (1991): 43–51.
Sutton, L.R., and S.A. Hinderliter. “Diazepam Abuse in Pregnant Women on Metha-
done Maintenance. Implications for the Neonate.”Clinical Pediatrics29 (1990):
108–11.
Willumeit, H.P., H. Ott, and W. Neubert. “Simulated Car Driving as a Useful Technique
for the Determination of Residual Effects and Alcohol Interaction after Short-
and Long-Acting Benzodiazepines.”Psychopharmacology, no. 1 (1984, Suppl.):
182–92.