Dipipanone 131create a rush of enjoyment that some persons prefer over heroin. In the 1980s
some British observers considered dipipanone abuse to be as much a problem
as abuse of methadone andmethylphenidate, with some addicts getting their
supplies legally from doctors. Rather little has been heard about the substance
since then, however.
Drug interactions.Dipipanone may interact badly with monoamine oxidase
inhibitors (MAOIs), which are substances found in some antidepressants and
other medication.
Cancer.Potential for causing cancer is unknown.
Pregnancy.Potential for birth defects is unknown. Authorities are uncertain
whether the drug passes into a nursing mother’s milk, but they believe the
level would be so low as to cause no harm to the infant. An infant can be
born dependent on the drug if the mother has been using it during the final
trimester of pregnancy.
Additional scientific information may be found in:
Bound, D., and S. Greer. “Psychotic Symptoms after Dipipanone.”Lancet2 (1978): 480.
Faull, C., et al. “Experience with Dipipanone Elixir in the Management of Cancer Re-
lated Pain—Case Study.”Palliative Medicine8 (1994): 63–65.
Posner, J., et al. “Effects of an Opiate on Cold-Induced Pain and the CNS in Healthy
Volunteers.”Pain23 (1985): 73–82.
Stewart, M.J., et al. “Forensic Toxicology in Urban South Africa.”Journal of Toxicology:
Clinical Toxicology38 (2000): 415–19.
Telekes, A., et al. “Effects of Triprolidine and Dipipanone in the Cold Induced Pain
Test, and the Central Nervous System of Healthy Volunteers.”British Journal of
Clinical Pharmacology24 (1987): 43–50.
Turnbull, A.R., and P. Isaacson. “Ischemic Colitis and Drug Abuse.”British Medical
Journal2 (1977): 1000.