152 Ethchlorvynol
drawal symptoms; in an infant these may include abnormal reflexes, ner-
vousness, and peevishness. Standard advice is to avoid ethchlorvynol during
pregnancy. Although the drug’s presence in milk of nursing mothers is un-
clear, the potential hazard of dosing infants through the milk makes nursing
inadvisable.
Additional scientific information may be found in:Flemenbaum, A., and B. Gunby. “Ethchlorvynol (Placidyl) Abuse and Withdrawal (Re-
view of Clinical Picture and Report of 2 Cases).”Diseases of the Nervous System
32 (1971): 188–92.
Garetz, F.D. “Ethchlorvynol (Placidyl). Addiction Hazard.”Minnesota Medicine 52
(1969): 1131–33.
Heston, L.L., and D. Hastings. “Psychosis with Withdrawal from Ethchlorvynol.”Amer-
ican Journal of Psychiatry137 (1980): 249–50.
Kripke, D.F., P. Lavie, and J. Hernandez. “Polygraphic Evaluation of Ethchlorvynol (14
Days).”Psychopharmacology(Berlin) 56 (1978): 221–23.
Kurt, T.L., G. Reed, and R.J. Anderson. “Pulmonary Edema after Intravenous Ethchlor-
vynol (Placidyl).”Veterinary and Human Toxicology24 (1982, Suppl.): 76–78.
Marshall, E. “Rehnquist’s Drug Dependence Poses Dilemma.”Science215 (1982):
379–80.
Yell, R.P. “Ethchlorvynol Overdose.”American Journal of Emergency Medicine8 (1990):
246–50.