The Encyclopedia of ADDICTIVE DRUGS

(Greg DeLong) #1

156 Ethylestrenol


drug is not recommended for men suffering from breast or prostate cancer.
The substance can worsen porphyria, a disease that can make people violent
and sensitive to light. Ethylestrenol has been used to help short youths grow
taller but if used incorrectly may instead terminate bone growth, preventing
young users from attaining the full adult stature that they would otherwise
have achieved. Effective usage to promote height requires careful medical su-
pervision.
Abuse factors.Some bodybuilders use ethylestrenol in hopes of promoting
muscle mass even though the substance is banned by international athletic
organizations.
Drug interactions.Rats that receive ethylestrenol are better able to survive
massive exposure tomeprobamateornicotineand high exposure to the in-
secticides paraoxon and parathion. Ethylestrenol also makes rats act less af-
fected byLSD. Ethylestrenol can counteract anesthesia actions of barbiturates,
diminish ulcers caused by the pain reliever indomethacin, and reduce conse-
quences of vitamin D overdose.
Cancer.Not enough scientific information to report.
Pregnancy.Pregnant women and nursing mothers are supposed to avoid
ethylestrenol. In rat experiments the drug masculinized female fetuses.
Additional scientific information may be found in:

Chakrabarti, R., and G.R. Fearnley. “Phenformin Plus Ethylestrenol in Survivors of
Myocardial Infarction: Three-Year Pilot Study.”Lancet2 (1972): 556–59.
Hecht, A. “Anabolic Steroids: Pumping Trouble.”FDA Consumer18 (September 1984):
12–15.
Kawashima, K., et al. “Virilizing Activities of Various Steroids in Female Rat Fetuses.”
Endocrinologia Japonica24 (1977): 77–81.
Kerrebijn, K.F., and A. Delver. “Ethylestrenol (Orgabolin): Effects on Asthmatic Chil-
dren during Corticosteroid Treatment.”Scandinavian Journal of Respiratory Dis-
eases68 (1969, Suppl.): 70–77.
Murchison, L. “Uses and Abuses of Anabolic Steroids.”Prescribers’ Journal26 (1986):
129–35.
Van Puymbroeck, M., et al. “17alpha-ethyl-5beta-estrane-3alpha, 17beta-diol, a Biolog-
ical Marker for the Abuse of Norethandrolone and Ethylestrenol in Slaughter
Cattle.”Journal of Chromotography. B, Biomedical Sciences and Applications 728
(1999): 217–32.
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