188 Glutethimide
posure to glutethimide exhibit abnormal behavior, but their own offspring
behave normally. Pregnant women have routinely received glutethimide for
insomnia, nausea, and vomiting. Humans with sufficient fetal exposure may
be born dependent on the drug. It has been used to ease labor. Nursing moth-
ers who take the drug may have enough glutethimide in their milk to make
their infants sleepy.
Additional scientific information may be found in:Bender, F.H., J.V. Cooper, and R. Dreyfus. “Fatalities Associated with an Acute Over-
dose of Glutethimide (Doriden) and Codeine.”Veterinary and Human Toxicology
30 (1988): 332–33.
DiGiacomo, J.N., and C.L. King. “Codeine and Glutethimide Addiction.”International
Journal of the Addictions5 (1970): 279–85.
Haas, D.C., and A. Marasigan. “Neurological Effects of Glutethimide.”Journal of Neu-
rology, Neurosurgery, and Psychiatry31 (1968): 561–64
Jones, A.H., and J.F. Mayberry. “Chronic Glutethimide Abuse.”British Journal of Clinical
Practice40 (1986): 213.
Kovacs, T. “[Acute Toxicological Cases during a Ten-Year Period in Our Clinic].”Orvosi
Hetilap[Hungarian Medical Journal] 143 (2002): 71–76. Abstract in English.
Mould, G.P., S.H. Curry, and T.B. Binns. “Interaction of Glutethimide and Phenobar-
bital with Ethanol in Man.”Journal of Pharmacy and Pharmacology24 (1972): 894–
99.
Reveri, M., S.P. Pyati, and R.S. Pildes. “Neonatal Withdrawal Symptoms Associated
with Glutethimide (Doriden) Addiction in the Mother during Pregnancy.”Clin-
ical Pediatrics16 (1977): 424–25.
Shamoian, C.A. “Codeine and Glutethimide; Euphoretic, Addicting Combination.”New
York State Journal of Medicine75 (1975): 97–99.