Methandrostenolone 283olone simply caused fluid swelling in tissues. Yet one more experiment mea-
sured increase in muscle mass among athletes using the substance but
detected no increase in strength.
Stock raisers administer methandrostenolone to promote sheep and cattle
growth.
Drawbacks.A case report warns that using the substance on girls can pro-
duce male qualities in voice while reducing female sexual characteristics; these
changes can be long-lasting and perhaps permanent. Although a skin cream
containingnandroloneis used to combat eczema, the same use of a cream
containing methandrostenolone has had serious consequences when applied
to girls, causing some female physical characteristics to diminish while mas-
culine ones appeared.
A case report attributed a 28-year-old bodybuilder’s heart disease and hard-
ening of the arteries to a dozen years of using methandrostenolone and other
steroids. Another case report blamed methandrostenolone alone for blockage
of blood vessels between heart and lungs in a 26-year-old bodybuilder. At-
tempts to treat the condition with the anti–blood clot drug warfarin became
complicated when the steroid boosted that drug’s actions.
When taking methandrostenolone daily, a person experienced delusions
and paranoia. Excessive self-confidence created by the drug inspired one user
to buy a $17,000 automobile on credit despite his inability to make payments.
After going off methandrostenolone the person sold the car, but upon resum-
ing the drug, he purchased a $20,000 vehicle. Medical literature also records
that a 22-year-old athlete using methandrostenolone andstanozololdevel-
oped feelings of powerfulness and aggression, accompanied by impatience.
Methandrostenolone apparently causes acne and is suspected of worsening
tics in Tourette’s syndrome. Men may experience urinary difficulty and low-
ered testosterone levels. The substance can bring on an attack of porphyria in
persons who suffer from that body chemistry disease, an affliction that some-
times involves violence and sensitivity to light.
Abuse factors.An opiatelike dependence was reported in a 23-year-old
bodybuilder who had been on a steady regimen including methandrosteno-
lone,oxymetholone, andoxandrolone. When given a drug that counteracts
opiate actions he quickly exhibited nausea, chills, dizziness, and headache—
classic flulike opiate withdrawal symptoms. When his supply of steroids
ceased he craved them and felt weary and depressed. Another case report
notes a bodybuilder who dosed extensively on methandrostenolone and other
steroids and experienced severe depression when he stopped.
Drug interactions.Not enough scientific information to report.
Cancer.Researchers examining reported deaths from a type of liver cancer
called hepatic angiosarcoma found a total of 168 throughout the United States
from 1964 to 1974, of which the investigators associated 1 with methandrosten-
olone (this individual was also a formeralcoholabuser, conduct that is no-
toriously hard on the liver). Methandrostenolone and other steroids are
suspected of causing kidney cancer in a 38-year-old bodybuilder.
Pregnancy.Mice studies indicate that the drug can produce lethal mutations
in sperm, causing pregnancy failure.
Additional scientific information may be found in: