288 Methaqualone
cates that diphenhydramine boosts the actions of methaqualone; some re-
search indicates that the antihistamine lengthens the time that a methaqualone
dose lasts. Adverse reactions have occurred when persons take the combina-
tion along with tricyclic antidepressants.
Additional information.Methaqualone anddiazepameach have the nick-
name “Ludes,” but the drugs are different substances.
Additional scientific information may be found in:Bailey, D.N. “Methaqualone Ingestion: Evaluation of Present Status.”Journal of Ana-
lytical Toxicology5 (1981): 279–82.
Brown, S.S., and S. Goenechea. “Methaqualone: Metabolic Kinetic and Clinical Phar-
macologic Observations.” Clinical Pharmacology and Therapeutics 14 (1973):
314–24.
“Evaluation of a Sedative-Hypnotic Agent; Methaqualone (Quaalude).”Journal of the
American Medical Association199 (1967): 749.
Falco, M. “Methaqualone Misuse: Foreign Experience and United States Drug Control
Policy.”International Journal of the Addictions11 (1976): 597–610.
Gerald, M.C., and P.M. Schwirian. “Nonmedical Use of Methaqualone.”Archives of
General Psychiatry28 (1973): 627–31.
Ostrenga, J.A. “Methaqualone—A Dr. Jekyll and Mr. Hyde?”Clinical Toxicology 6
(1973): 607–9.
Perry, C.D., et al. “The South African Community Epidemiology Network on Drug
Use (SACENDU): Description, Findings (1997–99) and Policy Implications.”Ad-
diction97 (2002): 969–76.
Roden, S., P. Harvey, and M. Mitchard. “Influence of Alcohol on the Persistent Effects
on Human Performance of the Hypnotics Mandrax and Nitrazepam.”Interna-
tional Journal of Clinical Pharmacology, Therapy and Toxicology15 (1977): 350–55.
Wetli, C.V. “Changing Patterns of Methaqualone Abuse. A Survey of 246 Fatalities.”
Journal of the American Medical Association249 (1983): 621–26.