BOK_FINISH_9a.indd

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the astrocycles and this could mean that glycolysis in the neurons themselves
might be less efficient since they normally do not perform the entire
glycolysis process, and this inefficiency would result in less ATP and more
heat. But since the body is in hyperfuel mode there is more glucose available
to convert...so the outcome would be both more energy (ATP) generated,
increased firing of action potentials, plus increased heat due to the inefficient
conversion to ATP.


  • Compounds with thermogenic activity are substances which foster the
    production of heat relative to the production of ATP. The main thermogenic
    compound is the thyroid hormone, thyroxin (T4). Thyroxin has the ability
    “uncouple” oxidative phosphorylation (less ATP production and more heat
    production) by enhancing the activity of glycerol-3-phosphate dehydrogenase
    and malic enzyme.

  • Kundalini heat is not exclusively caused by thermogenesis in brown fat,
    because otherwise the heat would be centered between the shoulder blades
    and around the kidneys etc... Although the extra adrenaline of sympathetic
    activation will increase brown fat energy production and increase lipolysis...
    one of the reasons we lose weight during our first awakening.

  • DHEA enhances the activity of three thermogenic enzymes: glycerol-3-
    phosphate dehydrogenase, malic enzyme and fatty acetyl CoA oxidase.


tHermoGenesis


Mitochondria are the organelles sometimes called the “powerhouses” of the
cell, where oxygen respiration occurs. As the energy powerhouses of the eukaryotic
cell mitochondria dutifully serve as the efficient source of adenosine triphosphate
(ATP) for cell function. ATP is an energy-rich molecule used throughout cells for
a variety of processes, and is largely produced in mitochondria by the breakdown
of energy-rich nutrients such as glucose. Mitochondria are responsible for creating
more than 90% of the energy needed by the body to sustain life and support
growth. ATP is the “energy currency” of the cell and is used to drive all energy
requiring reactions including the synthesis of proteins, carbohydrates and fats. It
also causes muscles to contract and nerves to conduct.
Mitochondria are found in high concentrations in high-energy producing
organs—such as the nerves, heart, liver, adrenals, GI tract, brain, muscles and
endocrine glands. Although some ATP is produced directly in a chemical reaction,
most ATP is synthesized by electron transport in the mitochondrion.
Nerve cells obtain ATP only through glucose catabolism in the presence of
oxygen. The mitochondria in the brain and the rest of the CNS uses glucose as
its fuel, the rest of the body’s mitochondria can use either glucose or fatty acids
for energy. The brain uses 25% of the energy of the body but constitutes only
2% of the mass. The production of energy from glucose and fatty acids occurs at
the cellular level with glycolysis (glucose metabolism) occurring in the cytosol of
the cell, while fatty acid oxidation in the mitochondria of the cell and most cells
involved with fatty acid metabolism are in the liver.

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