substrate for energy production, is an end product of both glycolysis and fatty
acid metabolism. Acetyl CoA, as a substrate in the Krebs cycle, produces NADH,
NADPH and FADH2, which are reducing agents that supply hydrogen atoms
or electrons in chemical reactions and are used for ATP production in the
mitochondria via a process called oxidative phosphorylation.
NADH is the reduced (electron-energy rich) coenzyme form of vitamin B3.
NADH is involved in all of these different cycles, as well as in the conversion of the
glycolytic cycle end product “pyruvate” into the beginning fuel of the Krebs’ citric
acid cycle. The energy from the broken chemical bonds is carried by the reducing
agents (electron donors NADH and FADH2) to the electron transport chain.
Electrons are passed from one protein to another in the electron transport chain,
releasing energy at each step. Some of the proteins in the electron transport chain
use this energy to pump protons (H+) across the inner mitochondrial membrane.
This creates an electrochemical gradient, or potential. The energy contained in this
gradient is used by an enzyme called ATP-synthetase to produce ATP.
thermogenic utilization of naDH: The oxidation of fatty acids also produces
NADH and FADH2. Each mole of NADH produces 3 ATP’s within the confines
of the mitochondria. NADH is also produced in the cytosol cell medium (outside
of the mitochondria) but needs to be transported into the mitochondria in order
to be converted to energy. This transport mechanism is called the “glycerol-3-
phosphate shuttle” and requires the enzyme glycerol-3-phosphate dehydrogenase
to catalyze the reaction. This “shuttle” requires energy and the end result is that
cytosolic NADH is only able to produce 2 ATP’s per mole and the rest of the
energy is released as heat.
Another possible source of metabolic heat is generated in the reaction which
converts malic acid (a Krebs cycle intermediate) to pyruvate and NADPH. This
conversion occurs in the cell cytosol and requires an enzyme called malic enzyme.
This reaction is important since it not only produces cytosolic NADPH but also
produces heat. http://www.neuro.wustl.edu/neuromuscular/alfindex.htm
Heat sHocK Proteins
Heat shock proteins (HSPs), or stress proteins, are a group of proteins that are
present in all cells in all life forms. They are induced when a cell undergoes various
types of environmental stress like heat, cold, oxygen deprivation, poisons or signals
from nerves or hormones. These heat shock proteins are sometimes called molecular
chaperones, because they protect and usher other protein molecules around in the
cell. They play an essential role in regulating normal protein equilibrium, that is the
balance between synthesis and degradation. Research has demonstrated that prior
heat shock protects the nervous system at the functional level of neurotransmission
and that specific stress-induced heat shock proteins are created tailored to elements
of the synapse. This might suggest that the heat of kundalini actually protects
synapses whose functionality must be preserved during stressful conditions to
prevent breakdown of communication in the nervous system.
The heating of the nervous system by kundalini could increase the production