Internal Medicine

(Wang) #1

0521779407-17 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:18


Peritoneal Tumors Peritonitis 1161

■peritoneal carcinomatosis: intraperitoneal chemotherapy advo-
cated by some
■ovarian cancer: surgical debulking and chemotherapy most promis-
ing
follow-up
n/a

complications and prognosis
■overall very poor: survival 70% at 1 month, 25% at 3 months,12% at
6 months, and 4% at 12 months after diagnosis of peritoneal carci-
nomatosis

PERITONITIS


MINDIE H. NGUYEN, MD


history & physical
History
■bacterial peritonitis common in ambulatory peritoneal dialysis (1.4
events per patient-year)
■tuberculous peritonitis: in the US, 50% of the cases are associated
with cirrhosis, usually alcoholic; in third-world countries, most cases
occur without underlying cirrhosis
■Fitz-Hugh-Curtis syndrome=Chlamydia (less commonly gonococ-
cus) peritonitis; actually a perihepatitis; very rare in men
■fungal peritonitis: usually due to Candida albicans and associated
with perforated viscus or ambulatory peritoneal dialysis
■peritoneal histoplasmosis, coccidioidomycosis, and cryptococcal
infection: rare in the US; usually seen in the setting of AIDS
■parasitic peritonitis: schistosomiasis, pinworms, ascariasis, strongy-
loidiasis, amebiasis; rare
■rare causes of peritonitis: connective-tissue diseases (lupus, pol-
yarteritis, and scleroderma); familial Mediterranean fever (very rare
in the US, common in Europe and in the Far East)

Signs and Symptoms
■peritoneal dialysis: abdominal pain and tenderness in 75% but fever
only in 33%
■Fitz-Hugh-Curtis syndrome: RUQ pain, fever, hepatic friction rub;
ascites may not be detectable clinically
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