Internal Medicine

(Wang) #1

0521779407-17 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:18


Peritonitis Persistent Vegetative State 1163

suspected dialysis-related cases and intestinal ischemia/perfor-
ation, respectively
■tuberculous peritonitis: 8 weeks of isoniazid, rifampin, and pyrazi-
namide, followed by 4 more months of isoniazid and rifampin
■Fitz-Hugh-Curtis: doxycycline usually curative
■fungal peritonitits: amphotericin B (intraperitoneal and intravenous
combination therapy) may be curative
follow-up
■repeat paracentesis to access improvement in peritonitis with
decreasing WBC
complications and prognosis
■recurrent infection is common and may require replacement or
removal of peritoneal catheter in dialysis patients
■fungal peritonitis more difficult to cure
■worse in AIDS patients

PERSISTENT VEGETATIVE STATE


MICHAEL J. AMINOFF, MD, DSc

history & physical
■Pt previously in coma from bihemispheric disease appears awake,
but w/o evidence of mental awareness or responsiveness
■Is totally dependent
■No evidence of mental activity
■Periods w/ opened eyes but no environmental contact
■May be decerebrate or decorticate posturing, recovery of brain stem
reflexes, but no purposive responses
■Pt has sleep-wake cycles
tests
■EEG abnormal but shows evidence of sleep-wake cycles in previously
comatose pt
differential diagnosis
■History of preceding coma distinguishes this disorder from de-
efferented state (“locked-in syndrome”) in which pt is conscious but
mute & quadriplegic
management
■Supportive care
■Discuss poor prognosis w/ family & consider withdrawal of support
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