Internal Medicine

0521779407-C03 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 20:54

414 Coronavirus/Common Cold Cough

Signs & Symptoms

■Upper respiratory infection

■Sneezing

■Coryza

■Sometimes low-grade fever

■Occasionally lower tract symptoms

tests

Specific

■Most strains cannot be isolated in diagnostic virology laboratory.

■Antibody assays not commercially available

■Electron Microscopy (EM) – viral particles can sometimes be visual-

ized by EM, but not routinely available

differential diagnosis

■Other respiratory viruses, particularly rhinovirus

■Allergies

management

■Good handwashing

■No vaccines available

specific therapy

■No specific therapy yet available

■Supportive

follow-up

n/a

complications and prognosis

n/a

Cough............................................

DARYA SOTO, MD

history & physical

History

■Time of onset, frequency, timing of cough:

➣Paroxysmal (pertussis)

➣Nocturnal (asthma, gastric reflux, chronic aspiration, pulmonary

edema)