Internal Medicine

(Wang) #1

P1: RLJ/OZN P2: PSB


0521779407-D-02 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:9


Dyspnea Echinococcosis 517

General Measures
■Additional tests based on clinical suspicion, pulmonary function
testing

specific therapy
■Aimed at treatable etiologies (see specific diseases)
■Severe dyspnea (eg, end-stage lung disease) may require oxygen,
noninvasive ventilation (BiPAP), and opiates

follow-up
■Careful coordination of care may be needed during extensive work-
up

complications and prognosis
■Depends on underlying cause

Echinococcosis......................................


J. GORDON FRIERSON, MD


history & physical
History
■Disease due toEchinococcus granulosisandEchinococcus multiloc-
ularis
➣Life cycle:E. granulosis: eggs shed by sheep dog are ingested by
sheep or man, develop into larval cysts, mainly in the liver; cysts
are eaten by dogs and larvae develop into tapeworm, which gives
off eggs
E. multilocularis: same cycle except hosts are foxes, wolves,
other carnivores, and intermediate hosts are voles, shrews,
mice. Arctic and alpine disease.
■Exposure: ingestion of eggs of either cestode through dirty hands,
food

Signs & Symptoms
■E. granulosis: usually silent until cyst in liver reaches 5 or more cm.
Then RUQ pain, or pain elsewhere, depending on where cyst is (most
are in liver or lung). Rupture or leak causes allergic reactions, occa-
sionally anaphylaxis.
■E. multilocularis: grows rapidly, pain is more frequent, generally in
liver
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