Internal Medicine

(Wang) #1

0521779407-13 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:15


926 Lung Fluke

■Other tests: Chest X-ray often shows scattered opacities in early stage,
later cysts, scarring, small effusions. Serology helpful, done by CIE
(at CDC).
differential diagnosis
■Pulmonary form: tuberculosis, other chronic infections, COPD, car-
cinoma
■During migration: other causes of abdominal pain

management
What to Do First
■Assess severity of infection, and look for ectopic disease (brain,
abdomen).

General Measures
■Determine source of infection, educate patient, ensure good nutri-
tion.
specific therapy
Indications
■All patients

Treatment Options
■Praziquantel for 3 days: generally curative.
Triclabendazole (compassionate use)

Side Effects & Complications
■May have abdominal pains, wheeze, relating to death of worms
➣Contraindications to treatment: absolute: allergy to medication
➣Contraindications to treatment: relative: none
follow-up
During Treatment
■Monitor symptoms.

Routine
■Check stools, sputum (if available) for ova 2–4 weeks after treatment.
Obtain chest X-ray at intervals.
complications and prognosis
■Main complication is ectopic worms, especially in brain, which can
cause seizures, headache, focal neurologic signs, coma. Treatment
is with praziquantel with steroid coverage. Abdominal worms can
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