chapter 13 Bacterial Pyoderma....................................
DEFINITION/OVERVIEW
Bacterial infections of the skin and adnexal structures.
Microbiome: mixed population of microorganisms that colonize the skin, gut, oral
cavity, and other sites: up to 90% of total cells in an individual may be microbial.
Pyoderma is a term used to describe any skin disease that is pyogenic (has pus);
commonly used in veterinary medicine to describe superficial and deep bacterial
infections.
ETIOLOGY/PATHOPHYSIOLOGY
Skin infections occur when the surface integrity of the skin has been broken, the skin
has become macerated (e.g., by chronic exposure to moisture), normal bacterial flora
have been altered, circulation has been impaired, and/or immunocompetency has been
compromised.
Primary types of cutaneous bacterial colonies: resident and transient.
Resident:
“Normal” bacteria found on “normal” skin that can multiply to establish and
maintain colonies
Normal skin flora (microbiome) vary with body site (greater diversity on haired
skin versus mucosal or mucocutaneous surfaces)
Serve as a component of the immune defense system (carry important func-
tional genes responsible for synthezing numerous metabolites that influence
host health)
Bacterial dysbiosis: alterations in the resident microbiome may influence disease
(cause or effect), i.e., atopic skin has a significantly less diverse bacterial and
fungal microbiome than does healthy skin
Alteration of the microbiome may allow for greater management of the specific
disease
Bacteria are located in the superficial epidermis and infundibulum of the hair
follicle and receive nutrients via sebum and sweat; these organisms live in sym-
biosis and help inhibit colonization by invading bacteria via bacteriocins
Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Small Animal Dermatology, Third Edition.
Karen Helton Rhodes and Alexander H. Werner.
©2018 John Wiley & Sons, Inc. Published 2018 by John Wiley & Sons, Inc.
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