512 DISEASES/DISORDERS
Canine leproid granuloma:
Cases have been associated with fly bites and may seasonally fluctuate; short coat
may predispose
Likely worldwide; most cases reported from Australasia and Brazil; United States
reported in California, Hawaii, and Florida
Most often seen in short-haired outdoor-housed large-breed dogs, especially
boxers (and their crosses), Staffordshire bull terriers, foxhounds, doberman pin-
schers, and German shepherds.
Systemic nontuberculous mycobacteriosis:
Also known as opportunistic or atypical mycobacteriosis
Sporadic disease that can affect dogs and cats of any age
Most patients are immunosuppressed or have concurrent systemic diseases
Exposure: routes of exposure in pulmonary and systemic disease are unknown
Pleuritis; localized or disseminated granulomas; disseminated disease, neuritis;
bronchopneumonia
Mycobacterial panniculitis; adult cats and dogs; infections follow trauma or bite
wound, resulting in inoculation of the subcutaneous fat; risk factor with obesity.
CLINICAL FEATURES
Tuberculosis:
Correlated with the route of exposure; major sites of involvement: oropharyngeal
lymph nodes, cutaneous and subcutaneous tissues of the head and extremities;
pulmonary system; gastrointestinal system
Dogs: respiratory, especially coughing; dyspnea uncommon
Cats: from contaminated milk: weight loss, chronic diarrhea, and thickened
intestines; from predation: cutaneous nodules, ulcers, and draining tracts
Dogs and cats: pharyngeal and cervical lymphadenopathy; unproductive effort
to vomit, ptyalism; tonsillar abscess; lymph nodes are visible or palpably firm,
fixed, tender; may ulcerate and drain
Cutaneous ulcers, nodules, plaques; yellow foul-smelling discharge
Pyrexia
Depression
Partial anorexia and weight loss
Hypertrophic osteopathy or hypercalcemia may occur
Disseminated disease: body cavity effusion; visceral masses; bone or joint
lesions; dermal and subcutaneous masses and ulcers; lymphadenopathy and/or
abscesses; CNS signs; sudden death
M. avium:failure to regrow hair after clipping in Abyssinian cats.
Feline leprosy syndrome:
Syndrome 1: initial localized nodules on limbs; progress rapidly, may ulcer-
ate and drain; aggressive clinical course; recurrence after surgical excision;
widespread lesions develop in several weeks; lack of systemic illness