546 DISEASES/DISORDERS
Central vestibular disease: differentiated by brainstem signs such as stupor and
lethargy.
Neoplasia: diagnosed by imaging studies.
Endocrinopathy: polyneuropathy and Horner’s syndrome associated with hypothy-
roidism.
Metronidazole toxicity.
Thiamine deficiency (cats).
Trauma.
Idiopathic vestibular disease (older dogs and middle-aged cats): diagnosis made by
exclusion of other causes.
DIAGNOSTICS
CBC/biochemistry/urinalysis: usually normal; may indicate a primary underlying dis-
ease (e.g., hypothyroidism, hematogenous spread of infection).
Allergy testing: restricted-ingredient food trial for cutaneous adverse reaction to food;
intradermal and/or serum allergy testing for atopy.
Neurologic examination: may indicate otitis interna.
Direct otoscopy: visualization of the external canal, tympanic membrane, and dorsal
and middle portions of the bulla (if tympanum ruptured).
Video-otoscopy:
Provides a magnified view of the canal
Improved visualization for diagnosis of otitis media
Permits more controlled sample collection
Allows direct visualization during cleaning, myringotomy, and surgical proce-
dures (including laser ablation and mass biopsy or removal) (Figure 37.23).
Imaging:
Radiographs: not highly sensitive for diagnosis of otitis media; useful for eval-
uating chronic changes; bullae should appear thin-walled and air-filled; bullae
may appear cloudy if filled with exudate; stenosis of external ear canal; thicken-
ing of bullae and petrous temporal bones with mineralization; presence of bone
lysis with osteomyelitis or neoplastic disease
Ultrasound: poor sensitivity in detecting otitis media compared with CT, MRI or
video-otoscopy
CT or MRI:
Detailed evidence of fluid or tissue density (e.g., polyp) in the bulla, adja-
cent tissues, or auditory tube
CT: useful for bony changes; stenosis or calcification of the canals; contrast
used to differentiate debris from soft tissues
MRI: useful for evaluation of the tympanic membrane and soft tissues; help-
ful to differentiate central versus peripheral vestibular disease.
Skin scrapings from pinnae: ectoparasites.
Dermatohistopathology: autoimmune disease, neoplasia, cerumen gland hyperplasia;
pinnae difficult to biopsy; avoid damaging auricular cartilage.