CHAPTER 41 PRE- AND PARANEOPLASTIC SYNDROMES 617
Cutaneous lymphocytosis:
Very rare; older dogs; median 8 years; range 5–14 years
Female predilection
Possible breed predilection: golden retriever, Shetland sheepdog, Chinese
crested, Welsh corgi
Cutaneous mastocytosis:
Rare; reported primarily in dogs under 1 year of age
Newfoundland, cocker spaniel, Labrador retriever, Jack Russell terrier,
other breeds
Nodular fasciitis:
No age, breed, or sex predilection. Canine paraneoplastic dermatoses:
Cutaneous (primary nodular) amyloidosis
Very rare; older dogs
Chinese shar-pei, cocker spaniels and beagles may be predisposed
Cutaneous mucinosis (secondary):Rare; may be associated with mast cell tumors
Multiple collagenous nevi: nodular dermatofibrosis:Rare; middle-aged dogs; range 3–7 years
German shepherd dog (autosomal dominant inheritance); golden retriever,
boxer, other breeds
Associated with renal cysts, cystadenomas, cystadenocarcinomas, and uter-
ine leiomyomas
Paraneoplastic pemphigus:
Very rare; too few reports to characterize
Superficial necrolytic dermatitis:
Rare; primarily old dogs (mean age 10 years)
Males possibly overrepresented
May have a heritable component in some breeds (shih tzu)
Predilection for medium and small breeds: West Highland white terrier,
Scottish terrier, American cocker spaniel, Shetland sheepdog, Lhasa apso,
border collie; syndrome also identified in large breeds
Lesions often precede systemic symptoms. Feline preneoplastic dermatoses:
Actinic keratoses:
No sex predilection
Age: usually older animals
Cutaneous lymphocytosis:Rare: older cats – median age 13 years; range 6–15 years
Female predilection (61%). Feline paraneoplastic dermatoses:
Pancreatic/hepatic paraneoplastic alopecia
Domestic shorthair cats
Older cats – median age: 13 years; range 7–16 years