chapter 43 Sebaceous Adenitis, Granulomatous........................
DEFINITION/OVERVIEW
An inflammatory disease process directed against the sebaceous glands (cutaneous
holocrine adnexal structures).
ETIOLOGY/PATHOPHYSIOLOGY
Idiopathic.
Genetic: inherited/congenital sebaceous gland destruction: autosomal recessive mode
of inheritance in standard poodle and Akita.
Immune mediated: cell-mediated reaction to a component of the sebaceous gland.
Metabolic: initial defect may be a keratinization disorder or an abnormality in lipid
metabolism leading to accumulation of toxic intermediate metabolites and sebaceous
gland destruction.SIGNALMENT/HISTORY
Young adult to middle-aged dogs.
Male predilection possible.
Two forms (predisposed breeds):
Long-coated: standard poodle, samoyed, Akita, German shepherd, hovawart,
havanese, Lhasa apsos,
Short-coated: vizsla, beagle, miniature pinscher.Seen in many purebreds as well as cross-bred dogs.
Rare in cats.
CLINICAL FEATURES
Long-Coated Dog Breeds
Lesions first observed along dorsal midline and dorsum of the head.
Change in hair color (especially poodles or due to adherent scales) (Figures 43.1,
43.2).
Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Small Animal Dermatology, Third Edition.
Karen Helton Rhodes and Alexander H. Werner.
©2018 John Wiley & Sons, Inc. Published 2018 by John Wiley & Sons, Inc.
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