CHAPTER 49 VIRAL DERMATOSES 713
Feline orofacial pain (FOP) syndrome (calicivirus): Burmese and Siamese cats predis-
posed, trigeminal neuralgia, unilateral intense pruritus, may be associated with oral
disease.Pseudorabies (alpha-herpesvirus): intense self-mutilating pruritus; pigs are main
reservoir; acute and fatal.
Causes – Dog
Canine papillomavirus (seven canine subtypes identified); oral or mucocutaneous
junction viral papillomas – young dogs or immunologically naive patients, associated
with cyclosporine drug use; exophytic horns – footpads of older dogs; multiple cuta-
neous papillomas – cocker spaniel and Kerry blue terrier predisposed; pigmented viral
plaques (chipapillomavirus) — multiple deeply pigmented small plaques on ventrum
and medial forelegs (pugs and miniature schnauzer predisposed); cutaneous inverted
papillomas – small, firm nodules with central indentation (Figures 49.15–49.22).Canine distemper (morbillivirus/paramyxovirus): nasodigital hyperkeratosis, “hard-
pad disease,” pustular dermatitis, fever, anorexia, oculonasal discharge, pneumonia,
diarrhea, neurologic disorders.Contagious viral pustular dermatitis (parapoxvirus): sheep and goat reservoir; pus-
tules, ulceration and crusts typically on the head; both dogs and cats affected; trans-
mission to humans possible.Pseudorabies (alpha-herpesvirus): intense self-mutilating pruritus; pigs are main
reservoir; acute and fatal.
Canine herpesvirus (herpesvirus): petechial hemorrhages on mucous membranes,
acute death in puppies, keratitis and conjunctivitis in adult dogs.
CLINICAL FEATURES
Crusts
Associated superficial bacterial folliculitis
Abscess
Paronychia
Poor wound healing
Seborrhea
Exfoliative dermatitis
Cutaneous horns
Exophytic papillomas
Gingivitis/stomatitis
Cutaneous or oral (MCJ) ulceration
Nasodigital hyperkeratosis
Pigmented macules or plaques
Progression to bowenoidin situcarcinoma (papillomavirus)