Biology Now, 2e

(Ben Green) #1
Pigs to the Rescue ■ 161

instructions behave the same. In humans, viral
DNA was integrated into the genome a long,
long time ago, and although it remains in the
human genome, it is no longer active. In pigs,
viruses entered and wove their DNA into the pig

Double or Nothing


DNA from viruses is actually present in all


mammalian genomes that we know of, includ-


ing the human genome, yet not all these viral


1


3


5


2


4


6


The chromatin
fiber folds and
loops, further
compacting
itself.

A nucleosome
consists of
DNA wound
around histone
proteins.

The loops coil
and coil until a
chromosome
is formed.

In the beads-
on-a-string
DNA structure,
nucleosomes
are the beads,
and adjoining
lengths of DNA
are the strings.

DNA is a
double-
stranded
nucleic acid.

The beads-
on-a-string
structures coil
around each
other to form a
chromatin fiber.

Figure 9.7


Chromosomes are meticulously organized DNA-protein complexes


The DNA double helix is continuously coiled and packaged around proteins until it is compacted into a


chromosome.


Q1: What are the structures that result from the first level of coiling around proteins called?

Q2: What makes up a “bead” and what makes up the “string” in the beads-on-a-string structure
of DNA?

Q3: What is the name for the structure that is more compact than the beads-on-a-string
structure but less compact than an actual chromosome?
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