B_T_2015_02_

(Michael S) #1
(a) variable region of heavy chain
(b) variable region of both heavy and light chain
(c) variable region of light chain
(d) constant region of both light and heavy chain.


  1. Which one of the following statements is correct with
    respect to immunity?
    (a) Preformed antibodies need to be injected to treat
    the bite by a viper snake.
    (b) The antibodies against small pox pathogen are
    produced by T-lymphocytes.
    (c) Antibodies are protein molecules, each of which
    has four light chains.
    (d) Rejection of a kidney graft is the function of
    B-lymphocytes.

  2. The sites on antigen that are recognized by antibodies
    and receptors present on T- and B-cells are
    (a) antigenic determinants
    (b) epitopes
    (c) paratopes
    (d) both (a) and (b).

  3. A person may die due to allergic reaction or an
    anaphylactic shock which is characterized by
    (a) constriction of peripheral blood vessel
    (b) blood capillaries become highly permeable causing
    loss of fluid from the blood
    (c) drastic increase in the blood pressure
    (d) all of the above.

  4. Bursa of Fabricius is an important organ of birds. This
    organ is associated with
    (a) generation of basophils
    (b) production of uric acid
    (c) metabolism of fatty acid
    (d) generation of B-cell.

  5. How does vaccination work?
    (a) The immune system produces antibodies which stay
    in the blood.
    (b) Memory lymphocytes are produced. They remain in
    the body to fight off any future infection with the
    live pathogen.
    (c) The dead pathogen stays in the body and constantly
    stimulates the immune system.
    (d) All of the above.

  6. Select the correct statement with respect to diseases
    and immunisation.
    (a) If due to some reason B and T lymphocytes are
    damaged, the body will not produce antibodies
    against a pathogen.
    (b) Injection of dead/inactivated pathogens causes
    passive immunity.


(c) Certain protozoans have been used in mass
production of hepatitis B vaccine.
(d) Injection of snake antivenom against snake bite is
an example of active immunisation.


  1. The Human Immuno deficiency Virus causes AIDS by
    (a) depleting CD 4 + T-helper lymphocytes
    (b) increasing CD 4 + T-helper lymphocytes
    (c) depleting CD 54 + T-helper lymphocytes
    (d) depleting CD 4 + T-helper erythrocytes.

  2. Which is an autoimmune disease?
    (a) Cancer
    (b) Asthma
    (c) Erythroblastosis foetalis
    (d) Rheumatoid arthritis

  3. A child stung by a bee experiences respiratory distress
    within minutes and lapses into unconsciousness. This
    reaction is probably mediated by
    (a) IgE antibody (b) sensitized T cells
    (c) complement (d) IgG antibody.

  4. Which of the following substances will not stimulate
    an immune response unless they are bound to a larger
    molecule?
    (a) Antigen (b) Virus
    (c) Hapten (d) Antibody

  5. A child has no detectable T or B cells. This
    immunodeficiency is most probably the result of a
    defect in
    (a) the thymus
    (b) the bursal equivalent
    (c) T cell-B cell interaction
    (d) stem cells originating in the bone marrow.

  6. The class of immunoglobulin present in highest
    concentration in the blood of a human newborn is
    (a) IgM (b) IgA
    (c) IgG (d) IgE.

  7. Human Immuno Deficiency Virus (HIV) has a protein
    coat and a genetic material which is
    (a) double stranded RNA
    (b) double stranded DNA
    (c) single stranded DNA
    (d) single stranded RNA.
    Answer KEy

  8. (d) 2. (a) 3. (d) 4. (a) 5. (a)

  9. (b) 7. (b) 8. (a) 9. (d) 10. (b)

  10. (d) 12. (d) 13. (a) 14. (a) 15. (d)

  11. (a) 17. (c) 18. (d) 19. (c) 20. (d)
    nn

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