Cell - 8 September 2016

(Amelia) #1

Meier, A., and So ̈ding, J. (2015). Automatic prediction of protein 3D structures
by probabilistic multi-template homology modeling. PLoS Comput. Biol. 11 ,
e1004343.


Meissner, M., Schlu ̈ter, D., and Soldati, D. (2002). Role of Toxoplasma gondii
myosin A in powering parasite gliding and host cell invasion. Science 298 ,
837–840.


Pappas, G., Roussos, N., and Falagas, M.E. (2009). Toxoplasmosis snap-
shots: global status of Toxoplasma gondii seroprevalence and implications
for pregnancy and congenital toxoplasmosis. Int. J. Parasitol. 39 , 1385–1394.


Peng, D., Kurup, S.P., Yao, P.Y., Minning, T.A., and Tarleton, R.L. (2014).
CRISPR-Cas9-mediated single-gene and gene family disruption in Trypano-
soma cruzi. MBio 6 , e02097-14.


Pieperhoff, M.S., Pall, G.S., Jime ́nez-Ruiz, E., Das, S., Melatti, C., Gow, M.,
Wong, E.H., Heng, J., Mu ̈ller, S., Blackman, M.J., and Meissner, M. (2015).
Conditional U1 gene silencing in Toxoplasma gondii. PLoS ONE 10 , e0130356.


Saeij, J.P.J., Boyle, J.P., Coller, S., Taylor, S., Sibley, L.D., Brooke-Powell,
E.T., Ajioka, J.W., and Boothroyd, J.C. (2006). Polymorphic secreted kinases
are key virulence factors in toxoplasmosis. Science 314 , 1780–1783.


Sander, J.D., and Joung, J.K. (2014). CRISPR-Cas systems for editing, regu-
lating and targeting genomes. Nat. Biotechnol. 32 , 347–355.


Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch,
T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., et al. (2012). Fiji: an
open-source platform for biological-image analysis. Nat. Methods 9 , 676–682.


Seeber, F., and Soldati-Favre, D. (2010). Metabolic Pathways in the Apicoplast
of Apicomplexa (Elsevier), pp. 161–228.


Seeber, F., Limenitakis, J., and Soldati-Favre, D. (2008). Apicomplexan mito-
chondrial metabolism: a story of gains, losses and retentions. Trends Parasitol.
24 , 468–478.


Shalem, O., Sanjana, N.E., Hartenian, E., Shi, X., Scott, D.A., Mikkelsen, T.S.,
Heckl, D., Ebert, B.L., Root, D.E., Doench, J.G., and Zhang, F. (2014).
Genome-scale CRISPR-Cas9 knockout screening in human cells. Science
343 , 84–87.


Sheiner, L., Demerly, J.L., Poulsen, N., Beatty, W.L., Lucas, O., Behnke, M.S.,
White, M.W., and Striepen, B. (2011). A systematic screen to discover and
analyze apicoplast proteins identifies a conserved and essential protein import
factor. PLoS Pathog. 7 , e1002392.


Shen, B., Brown, K.M., Lee, T.D., and Sibley, L.D. (2014). Efficient gene disrup-
tion in diverse strains of Toxoplasma gondii using CRISPR/CAS9. MBio 5 ,
e01114-14.
Sidik, S.M., Hackett, C.G., Tran, F., Westwood, N.J., and Lourido, S. (2014).
Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9.
PLoS ONE 9 , e100450.
Simske, J.S. (2013). Claudins reign: the claudin/EMP/PMP22/gchannel pro-
tein family in C. elegans. Tissue Barriers 1 , e25502.
Soldati, D., and Boothroyd, J.C. (1993). Transient transfection and expression
in the obligate intracellular parasite Toxoplasma gondii. Science 260 , 349–352.
Subramanian, A., Tamayo, P., Mootha, V.K., Mukherjee, S., Ebert, B.L., Gil-
lette, M.A., Paulovich, A., Pomeroy, S.L., Golub, T.R., Lander, E.S., and Me-
sirov, J.P. (2005). Gene set enrichment analysis: a knowledge-based approach
for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA
102 , 15545–15550.
Taylor, S., Barragan, A., Su, C., Fux, B., Fentress, S.J., Tang, K., Beatty, W.L.,
Hajj, H.E., Jerome, M., Behnke, M.S., et al. (2006). A secreted serine-threonine
kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii.
Science 314 , 1776–1780.
Treeck, M., Zacherl, S., Herrmann, S., Cabrera, A., Kono, M., Struck, N.S., En-
gelberg, K., Haase, S., Frischknecht, F., Miura, K., et al. (2009). Functional
analysis of the leading malaria vaccine candidate AMA-1 reveals an essential
role for the cytoplasmic domain in the invasion process. PLoS Pathog. 5 ,
e1000322.
Wang, T., Wei, J.J., Sabatini, D.M., and Lander, E.S. (2014). Genetic screens in
human cells using the CRISPR-Cas9 system. Science 343 , 80–84.
Wang, T., Birsoy, K., Hughes, N.W., Krupczak, K.M., Post, Y., Wei, J.J.,
Lander, E.S., and Sabatini, D.M. (2015). Identification and characterization of
essential genes in the human genome. Science 350 , 1096–1101.
Wellems, T.E., Walker-Jonah, A., and Panton, L.J. (1991). Genetic mapping of
the chloroquine-resistance locus on Plasmodium falciparum chromosome 7.
Proc. Natl. Acad. Sci. USA 88 , 3382–3386.
Winzeler, E.A., Shoemaker, D.D., Astromoff, A., Liang, H., Anderson, K., An-
dre, B., Bangham, R., Benito, R., Boeke, J.D., Bussey, H., et al. (1999). Func-
tional characterization of the S. cerevisiae genome by gene deletion and par-
allel analysis. Science 285 , 901–906.
World Health Organization (2014). World Malaria Report.http://www.who.int/
malaria/publications/world_malaria_report_2014/en/.

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