Figure S3. Neutralizing Activity in the Serum of Sequentially Immunized GLHL121 and MutHGLL121 Knockin Mice, Related toFigure 3
Purified Igs from one GLHL121 and 1 MutHGLL121 mice were tested for neutralization in a TZM-bl assay against 56 Tier 2 HIV-1 isolates of different clades. The
human PGT121 bNAb was tested in parallel for comparison. IC 50 < 0.096 in red; 0.096- 0.5 in orange; 0.5- 4 in yellow; > 4 green; not detectable (ND) in gray; not
tested indicated by a dash.
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