The Human Brain During the Third Trimester

ClaustruClaustrumm

PutamenPutamen

PutamenPutamen

FFoorrnniixx

Forn

ix

Forn

ix

Ex

ter

nal

cap

sule

Ex

ter

nal

cap

sule

Ext

ern

al^ c

aps

ule

Ext

ern

al^ c

aps

ule

External

capsule

External

capsule

Caudate

(tail)

Caudate

(tail)

P

re

te

ct

u

m

P

re

te

ct

u

m

Pr

etectum

Pr

etectum

Subiculum

Superior colliculus

Optic nerve layer

Superficial gray layer

Deep gray layer

Middle gray layer

Middle white layer

Deep white layer

Zonal layer

Cerebral

aqueduct

Cere bral

aqueduct

Subcommissural orga n

Lateral

fissure

Lateral fissure

Cl

au

str

um

Cl

au

str

um

IInnssuulalarr ggyyrruuss

Insu

lar^ g

yrus

Insu

lar^ g

yrus

Stria

terminalis

Stria

terminalis

BBA SAL GANGLIASAL GANGLIAA

THALAMUSTHALAMUS

Ventral

posterolateral

nucleus

Ventral

posterolateral

nucleus

PulvinarPulvinar

Third

ventricle

POSTERIOR

COMPLEX

POSTERIOR

COMPLEX

Periventricul

ar nuclei

Periventricul

ar nuclei

Mammillothalamic

tract

Mammillothalamic

tract

La

ter

al

(^) m
igr
ato
ry
(^) str
ea
m
La
ter
al
(^) m
igr
ato
ry
(^) str
ea
m
C
en
tr
om
ed
ia
n
nu
cl
eu
s
C
en
tr
om
ed
ia
n
nu
cl
eu
s
Diagonal band of Broca
(vertical limb)
Diagonal band of Broca
(vertical limb)
Forel's
fields
Forel's
fields
Dorsomedial
nucleus
Dorsomedial
nucleus

A

n

te

ri

o

r^

co

m

m

is

su

re

A

n

te

ri

o

r^

co

m

m

is

su

re

Parahippocampal gyrus

Subc

allos

al are

a

Subc

allos

al are

a

Co

rp

us

(^) c
all
os
um
(r
os
tr
um
)
Co
rp
us
(^) c
all
os
um
(r
os
tr
um
)
Nucleus
accumbens
Nucleus
accumbens
Nucleus
accumbens
Nucleus
accumbens
G
lo
b
u
s
p
allid
u
s
(in
te
r
n
a
l se
g
m
en
t)
G
lo
b
u
s
p
a
llid
u
s
(in
te
rn
a
l se
g
m
en
t)
CE
N
TR
A
L
C
O
M
PL
EX
CE
N
TR
A
L
C
O
M
PL
EX

PE

RIV

ENTR

ICULARCOM

PLE

X

PE

RIV

ENTR

ICULARCOM

PLE

X

Paraventricular

nucleus

Paraventricular

nucleus

HYPOHYPOTHALAMUSTHALAMUS

Median preoptic nucleus

AnterAnteromedial nucleuomedial nucleuss

A

NT

ER

IO

R

C

OM

PL

EX

A

NT

ER

IO

R

C

OM

PL

EX

Ansa

lenticularis?

Ansa

lenticularis?

Ansa

lenticularis?

Ansa

lenticularis?

Med

forebra ial

in (^) b
undl
e?
Med
forebra ial
in (^) b
undl
e?
Med
ial
fore
bra
in^ b
und
le?
Med
ial
fore
bra
in^ b
und
le?
Primary
olfactory
cortex
(piriform)
Primary
olfactory
cortex
(piriform)
Primary
olfactory
cortex
(piriform)
Primary
olfactory
cortex
(piriform)
G
lo
b
u
s
p
a
ll
id
u
s
(e
x
te
rn
al
seg
men
t)
G
lo
b
u
s
p
a
ll
id
u
s
(e
x
te
rn
al
seg
men
t)

M

e

d

u

ll

a

r

y

la

m

in

a

M

e

d

u

ll

a

r

y

la

m

in

a

Late

ralhypothalamic

area

Late

ralhypothalamic

area

C

en

tr

al

la

te

ra

ln

uc

le

us

C

en

tr

al

la

te

ra

ln

uc

le

us

V

en

tr

a

lm

ed

ia

ln

uc

leu

s

V

en

tr

a

lm

ed

ia

ln

uc

leu

s

Ventral posteromedial

nucleus

Ve ntral posteromedial

nucleus

Medial

geniculate

body

Medial

geniculate

body

R

E

T

IC

U L A R B E L T

R

E

T

IC

U L A R B E L T

V E N T R A L

CO

MPLEX

V E N T R A L

CO

MPLEX

Lateral

geniculate

body

Lateral

geniculate

body

C

e

re

b

ra

l

p

e

d

u

n

cl

e

C

e

re

b

ra

l

p

e

d

u

n

cl

e

S

u

b

th

al

am

ic

n

u

cl

eu

s

S

u

b

th

al

am

ic

n

u

cl

eu

s

R

e

t

i

c

u

l

a

r

n

u

c

le

u

s

R

e

t

i

c

u

l

a

r

n

u

c

le

u

s

Z

o

n

a

in

c

e

r

ta

Z

o

n

a

in

c

e

r

ta

S

U B T H A L A M U S

S

U B T H A L A M U S

Basal nucleus

of Meynert

Basal nucleus

of Meynert

Ve

nt

ra

l^ s

tri

atu

m

Ve

nt

ra

l^ s

tri

atu

m

SU

BS

TA

N

T

IA

IN

N

O

M

IN

A

T

A

SU

BS

TA

N

T

IA

IN

N

O

M

IN

A

T

A

GlobGlobus pallidusus pallidus

Ex

tern

al (^) c
aps
ule
Ex
tern
al (^) c
aps
ule
Central
gray
Central
gray
Lateral migratory stream
(infiltrates the claustrum
and the external capsule)
Lateral migratory stream
(infiltrates the claustrum
and the external capsule)
White matter
Layer I
Cortical plate
Subpial granular layerSubpial granular layer Germinal and transitional structuGerminal and transitional structurres ines in italicsitalics
Meyer's loop
(visual radiation)
Meyer's loop
(visual radiation)
In
te
rn
al
(^) ca
ps
ul
e
(a
nt
er
io
r
lim
b)
In
te
rn
al
(^) ca
ps
ul
e
(a
nt
er
io
r
lim
b)
Inte
rnal capsul
e
(posterior limb)
Inter
nal capsul
e
(posterior limb)
Te mporal neuroepithelium
and subventricular zone
Te mporal stratified
transitional field
Fo rnical glioepithelium
PPo sterior striatal neuroepithelium and subvosterior striatal neuroepithelium and subventricular zoneentricular zone
Alve ar glioepithelium
Subgranular zone
HIPPOCAMPUHIPPOCAMPUSS
Strionuclear
glioepithelium
Strionuclear
glioepithelium
Interhemispheric fissure
Callosal glioepithelium
Rostral migratory stream
(source area)
Accumbent neuroepithelium
and subventricular zone
(infiltrated by the
rostral migratory stream)
Ventral tenia tecta
MIDBRAIMIDBRAINN
TECTU
M
TECTU
M
Lateral ve ntricle
Choroid plexus
Dentate gyrus
Ammon's horn
Diencephalic (thalamic) glioepithelium/ependyma
Mesencephalic glioepithelium/ependyma
Diencephalic (hypothalamic)
glioepithelium/ependyma
Diencephalic (hypothalamic)
glioepithelium/ependyma
PLATE 137B